Changes in some peripheral blood immune parameters of patients with chronic periodontitis among servicemen of the armed forces of Ukraine

Abstract

The state of chronic periodontitis among servicemen of the Armed Forces of Ukraine remains extremely urgent. Therefore a group of servicemen with chronic periodontitis and its complications was taken. In addition, a control group of servicemen was used to compare the results. Investigated problem: in this article, the diagnosis was considered due to the use of immunological studies of peripheral blood of sick servicemen of the Armed Forces of Ukraine with chronic periodontitis, as well as its complications. The study of the features of immunological parameters in peripheral blood was performed. The main scientific results: according to the obtained data, there is a relative suppression of immunity among servicemen with chronic periapical infection compared with servicemen of the control group. According to our data, the main lymphocyte subpopulation of peripheral blood are CD8 and CD4/CD8; CD19+(B-lymphocytes) and CD3-HLA+; CD4 and CD4/CD8, which reflect inflammatory processes in the body. These indicators are closely interrelated. The area of practical use of the research results: these results of research can be applied to students’ training at stomatology faculties, in stomatology practice, to research into the immunological status of patients with chronic periodontitis and its complications. Innovative technological product: it is the first time the study of the immunological status of peripheral blood during chronic periapical infections among servicemen has been performed. Scope of the innovative technological product: this study can be used in the diagnosis and treatment of chronic periodontitis in dental practice, as well as in the research to compare the results of the immunological state of peripheral blood.